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Depresia severa (episodul depresiv sever) reprezinta o forma grava a tulburarii depresive majore, in care simptomele sunt foarte intense si pot interfera cu functionarea zilnica。

Se estimeaza ca 1 persoana din 5 a suferit macar un episod de depresie pe parcursul vietii, iar riscul creste de 4 ori in cazul varstnicilor (dupa varsta de 65 de ani).。

In general, medicatia este recomandata pentru cazurile de depresie severa si cronica. O analiza realizata de National Institute for Health and Care Excellence din Regatul Unit a descoperit ca inhibitorii selectivi de recaptare a serotoninei。

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